Here's an example: Upon graduation from an aeronautical engineering program, Joan C. accepted a high-paying job with an airplane manufacturer. She hated it--'the work was boring, and I didn't feel like my individual contribution would ever make much of a difference.'
So Joan took a big gamble: She quit, and even though many people doubtless thought she was crazy to leave such a 'great job', she reinvented her career around her interest in the world and her desire to help others.
Today, motivated by her passion for her work, she is a successful administrator for a nonprofit agency that provides health care in developing countries. The change undoubtedly cost her some earnings, but over the long term she ended up on a better and more personally rewarding track.