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Art et sommeil/rêves
Articles scientifiques divers
Hors Série le Rêve 1996
Michel Jouvet (avant 1966)
Michel Jouvet
Articles scientifiques divers
Afferent projections to the rat locus coeruleus demonstrated by retrograde and anterograde tracing with cholera-toxin B subunit and Phaseolus vulgaris leucoagglutinin
Pierre Herve Luppi, Gary Aston-Jones, Hideo Akaoka, Guy Chouvet and Michel Jouvet - Neuroscience 65 (1) : 119-160 (1995)
Thème : Articles scientifiques divers
The aim of this study was to examine the afferents to the rat locus coeruleus by means of retrograde and anterograde tracing experiments using cholera-toxin B subunit and phaseolus leucoagglutinin. To obtain reliable injections of cholera-toxin B in the locus coeruleus, electrophysiological recordin...
Human insulin gene insertion in mice. Effects on the sleep-wake cycle?
Jean-Louis Valatx, Philippe Douhet and Danielle Bucchini - J. Sleep Res. 8, Suppl. 1, 65-68 (1999)
Thème : Articles scientifiques divers
Recently, insulin synthesis and the presence of an insulin receptor have been demonstrated in the brain. Intracerebroventricular infusion of insulin causes a selective increase in the amount of slow-wave sleep. In the present study, the sleep-wake cycle of transgenic mice, with or without habenular ...
The Brain Histaminergic System and arousal mechanisms
Lin J. S. - FrenchCorner
Thème : Articles scientifiques divers
The relationship between histamine and sleep goes back as early as the 1930's when antihistamines were discovered in France. This class of drugs, now designated as H1-receptor antagonists, has notoriously been known to cause sedation and drowsiness in man when used in the treatment of allergies. How...
The Discovery of Cholera-Toxin as a Powerful Neuroanatomical Tool
Pierre Herve Luppi - FrenchCorner
Thème : Articles scientifiques divers
For thirty years, the advances made in our lab in neural mechanisms responsible for the generation of the sleep-waking cycle have been obtained by a multidisciplinary approach and the development of new methods of investigation. Indeed, physiological, neuroanatomical and pharmacological studies have...
Iontophoretic application of unconjugated cholera toxin B subunit (CTb) combined with immunohistochemistry of neurochemical substances: a method for transmitter identification of retrogradely labeled neurons
Pierre-Herve Luppi, Patrice Fort and Michel Jouvet - Brain Res. 534 (1-2) : 209-224 (1990)
Thème : Articles scientifiques divers
in this report, we demonstrate that cholera-toxin b subunit (ctb) is a very sensitive retrograde tracer in the central nervous system when recognized by streptavidin-peroxidase immunohistochemistry. we further show that: (1) injection of a small volume of ctb gives rise to small sharply defined inje...