10 December, 2008
Volume 60, Issue 5

X cover popup

Volume 60, Issue 5

On the cover: In this issue Neuron, Miyawaki et al. (pp. 915–929) present a method for free visual image reconstruction using fMRI signals recorded from the human visual cortex. The authors show that arbitrary visual images can be accurately reconstructed on a single-trial basis by combining local image decoders that predict local contrasts of multiple scales from fMRI activity patterns. The cover image represents visual image reconstruction from the human brain. The images printed on the film are based on the actual reconstruction results for the letters “n” - “e” - “u” - “r” - “o” - “n” and other geometric shapes (see Figure 2 in the article). The background texture consists of the contrast patterns of presented images.

Neuron Comments

  • Submit comments on any research or review article by sending an e-mail to Neuron Comments. Pending editorial approval, comments will be posted with the article on the Neuron website. For further information please refer to our Guidelines.

Podcast Interview

  • The most recent Cell Podcast features an interview with Dr. Elizabeth Phelps of New York University. Dr Phelps explains how the human brain controls responses to fearful memories and the implications for treating stress disorders. The interview starts at minute 33:30.

Most Read Papers

  • These are the most read papers by download from the Neuron website for the last 30 days.

In the News

  • Read coverage of recent Neuron articles in the popular press.

Featured Meeting

“From Mechanisms to Medicine”

The Second Florida Fragile X Young Investigator Research Conference
Sunday, April 19 – Tuesday, April 21, 2009 in West Palm Beach, Florida

The conference provides a unique forum for up and coming Fragile X investigators to present their own research, perspectives and ideas. Conference highlights include selected oral presentations, a poster session, speakers from private industry and public agencies and three cash awards of $1,250 each for the best oral presentations. Two cash awards of $750.00 each for the best poster presentations.

Register at www.FragileX.org

Sponsored by the National Fragile X Foundation And Scripps Florida/The Scripps Research Institute. Scientific Organizing Committee: Gary Bassell, Emory University; David Nelson, Baylor College of Medicine; Giovanni Neri, Catholic University of Rome; Karen Usdin, National Institutes of Health; Claes Wahlestedt, Scripps Florida. Click here for more information.


Featured Article | Across the Grid Field FREE
Garden et al. show that synaptic integration due to HCN and leak K+ channels in the entorhinal cortex aligns with spatial grid fields. Preview by Narayanan and Johnston.
Neuron Review | Mitochondria in Disease FREE
Mattson et al. review key functions played by mitochondria, organelles responsible for ATP generation, in the regulation of neural plasticity and neurological disease states.
On the Cover | Decoding the Mind's Eye
Miyawaki et al. investigate how visual images can be accurately reconstructed from fMRI activity patterns in human visual cortex as a means to decode perceptual states.


Behavior | Insights into Repetitive Behavior
Hoeffer et al. show that mice defective for FKBP12 and mTOR signaling exhibit repetitive behaviors, suggesting a role for this pathway in neurological disorders.
Systems | Neural Coding of Somatosensation
Petersen et al. examine how tactile information from the whisker system is encoded in the somatosensory system with individual neurons encoding diverse stimulus features.
Chemical Biology | Virtual Odorant Screen
Triballeau et al. employ a computational high-throughput screening strategy to discover novel high affinity agonists and in vivo odorants of olfactory receptors.


Neuron has an established history of high impact and insightful review articles and issues and has also been a leading force in the community to feature technological advances, with our Neurotechniques, and their expert explanation, with our Primers. Now we collect together in one online archive the best of Neuron’s review material.

Reviews Primers
Special Issues Neurotechniques



2008 marks Neuron’s twentieth anniversary. To celebrate this milestone we have commissioned a special issue to reflect on both the history of the journal and some of the notable advances in neuroscience over the last several remarkable decades. In celebration of our anniversary, all content for this special issue is free to our online readership.

Editorial | Table of Contents


In commemoration of the journal’s beginnings, we invited authors of research articles in the first issue of Neuron to look back at their original paper and comment on how the field has evolved since then. The first issue of the journal set a high standard and it is a testimony to the prescience of the journal’s founding editors — Zach Hall, A.J. Hudspeth, Eric Kandel, and Louis Reichardt — that the topics covered in the Volume 1, Issue 1 continue to be relevant even today.

First Issue Table of Contents | Reflections


With NeuroViews, the journal introduces a new review format aimed at discussion of issues at the intersection of neuroscience and society.

Gazzaniga overviews the emerging intersections between neuroscience and the law.

The relationship between neuroscience and philosophy is explored by Chuchland.

Camerer discusses the goals of Neuroeconomics and the means for achieving them.

Altevogt, Hanson & Leshner introduce “Molecules to Minds: Grand Challenges.”


In this series of Perspectives, we asked researchers to discuss the state of their respective fields looking back, forward, and within, and offer their unique insight into the future trajectory of neuroscience.

Abbott reviews theoretical neuroscience and how it has and can shape neuroscience.

Lichtman and Smith introduce tools at the intersection of imaging and neuroscience.

What are neural stem cells good for? Kokovay, Shen & Temple discuss their promise.

Dolan reflects on the rapid growth of neuroimaging of cognition as a dominant field

The diversity of brain plasticity mechanisms are reviewed by Nelson and Turrigiano.

Bezanilla offers a personal history on the historical development of ion channel field.

Donoghue explains how neural interface systems will bridge neuroscience and clinic.

Sudhof and Malenka on strategic challenges facing next generation neuroscientists.

Miller and Wilson on the impact of multiunit technology for understanding behavior.

Barres suggests that fully understanding glia is critical to conceptualizing the brain.

Frith and Frith propose an explicit/implicit processing framework for social cognition.

The molecular biology of gene expression in the CNS is reviewed by Qiu and Ghosh.