December, 2008
Volume 18, Issue 12

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Volume 18, Issue 12

Microtubules (MTs) have indispensable roles in cellular architecture, movements and division. Linear bundles are a prominent feature of MT arrays in many differentiated cell types such as neurons, and in plant and fungal arrays. The behaviour and organization of MTs within bundles is not well understood. On pp. 580–586, Scott Bratman and Fred Chang examine two emerging mechanisms for maintaining bundles of dynamic MTs: first, MT nucleation from pre-existing MTs by means of g-tubulin-containing complexes; and, second, MT ‘rescue’ by the stabilizing protein CLASP. How the cell senses how many MTs are present in each bundle and how many bundles there are in each cell is still under investigation. Cover design by Philip Paternall.



Editorial Team

  • Editor
    C. Rose Hosking
  • Executive Editor, Cell Biology
    Deborah Sweet
  • Production Editor
    Jennifer Key
  • Editorial Assistant
    Damien Robertson
  • Illustrations and Design
    Lara Crow
    Mat McCutcheon
    Philip Patenall
    Neill Sharp

Featured Article

E2F – at the crossroads of life and death
Shirley Polager , and Doron Ginsberg
10.1016/j.tcb.2008.08.003
Abstract | |


About Trends in Cell Biology

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Most Read Articles

These are the five most downloaded papers for the 30 days preceding. See full list of most read articles

E2F – at the crossroads of life and death
Shirley Polager, Doron Ginsberg
10.1016/j.tcb.2008.08.003
Summary | |
Decoding the quantitative nature of TGF-β/Smad signaling
David C. Clarke, Xuedong Liu
10.1016/j.tcb.2008.06.006
Summary | |
Dividing the workload at a eukaryotic replication fork
Thomas A. Kunkel, Peter M. Burgers
10.1016/j.tcb.2008.08.005
Summary | |
Canonical and non-canonical JAK–STAT signaling
Willis X. Li
10.1016/j.tcb.2008.08.008
Summary | |
Breaching the basement membrane: who, when and how?
R. Grant Rowe, Stephen J. Weiss
10.1016/j.tcb.2008.08.007
Summary | |