December, 2008
Volume 19, Issue 10

X cover popup

Volume 19, Issue 10

The sleep–wake cycle is controlled by hypothalamic circuits. Signalling through these circuits is affected by the metabolic hormones leptin and ghrelin, connecting the sleep cycle with metabolism. On pages 362–370 of this issue, Adamantidis and de Lecea discuss the recent evidence showing that sleep and energy homeostasis are intertwined, highlighting the connectivity between neuronal circuits in the hypothalamus. The cover depicts a camping scene with people sleeping and eating under the same sky (hypothalamus), with the constellations representing the neurons activated in these circuits and the comets the hormones. Illustration by Yvonne Blanco.

Editorial Team

  • Editor
    Susanne Tranguch
  • Executive Editor, Molecular Medicine
    Charlotte Wang
  • Production Editor
    Kirsty Strawbridge
  • Editorial Assistant
    Katherine Wright
  • Illustrations and Design
    Mat McCutcheon
    Yvonne Blanco
    Neill Sharp
  • Advisory Editor
    Kevin J Catt
  • Founding Advisory Editor
    Nicholas S. Halmi

Featured Article

Insulin resistance, inflammation, and non-alcoholic fatty liver disease
Herbert Tilg , and Alexander R. Moschen
10.1016/j.tem.2008.08.005
Abstract | |


About Trends in Endocrinology and Metabolism

Trends in Endocrinology and Metabolism, with its polished, concise and readable reviews, Research News, Meeting reports and discussions of topics at the cutting edge of endocrinology, covers both clinical and research aspects of the field, from state-of-the-art treatments of endocrine diseases to new developments in molecular biology, thus serving as an invaluable source of information for researchers, clinicians, lecturers, teachers and students. Commissioned clinicians and researchers report on advancements in reproductive endocrinology, developmental endocrinology, metabolism, biochemistry, diabetes and insulin action, thyroid hormone action, obesity, neuroendocrinology, molecular and cellular biology, and a host of other areas. From resident to experienced clinician, post-doctoral fellows to lab director, graduate student to professor - all will benefit from and enjoy reading this informative publication.

Reviews and Opinion articles form the foundation of each monthly issue. Reviews are invited from leading researchers in a specific field and objectively chronicle recent and important developments. Opinion articles provide a forum for debate and hypothesis. The research focus section includes short articles highlighting topical issues and recent research papers of particular note, as well as articles reporting on groundbreaking technical advances.

Most Read Articles

These are the five most downloaded papers for the 30 days preceding. See full list of most read articles

Insulin resistance, inflammation, and non-alcoholic fatty liver disease
Herbert Tilg, Alexander R. Moschen
10.1016/j.tem.2008.08.005
Summary | |
ERRα: a metabolic function for the oldest orphan
Josep A. Villena, Anastasia Kralli
10.1016/j.tem.2008.07.005
Summary | |
Is mitochondrial dysfunction a cause of insulin resistance?
Nigel Turner, Leonie K. Heilbronn
10.1016/j.tem.2008.08.001
Summary | |
Lipoatrophy Revisited
Marc L. Reitman, Elif Arioglu, Oksana Gavrilova, Simeon I. Taylor
Summary | |
Tissue-specific glucocorticoid action: a family affair
Katherine L. Gross, John A. Cidlowski
10.1016/j.tem.2008.07.009
Summary | |