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Un anticorps humain pour combattre les grippes

"Une équipe multidisciplinaire américaine de la Harvard Medical School (Boston, Massachusetts) et des Centers for Disease Control and Prevention (Atlanta, Georgia) vient de publier dans la revue britannique Nature Structural and Molecular Biology des résultats expérimentaux encourageants dans la lutte contre les virus de grippe.

Le travail est confiné pour le moment au domaine de l'expérimentation animale : l'équipe de biologistes américains a découvert un anticorps humain capable, lors d'expérimentations avec la souris, de neutraliser plusieurs sous-types du virus de la grippe, y compris le H5N1, responsable de l'épizootie de grippe aviaire hautement pathogène qui sévit au­tour du globe depuis 2003.

Rien en l'état, pour la communauté scientifique française concernée, ne permet de penser que ces résultats préliminaires puis­­sent un jour être transposés en clinique humaine, ni qu'un vaccin «universel» puisse être vraiment mis au point contre la grippe.

Il faut d'ailleurs rappeler qu'un essai humain sur volontaires sains d'un anticorps monoclonal du même genre, le Supermab, utile contre des cancers, avait en 2006 tourné au drame, six volontaires hospitalisés en réanimation avec des défaillances aiguës multi-organiques ayant failli mourir après une seule injection du produit (testé pourtant avec succès chez l'animal)..."

Source:http://www.lefigaro.fr/sante/2009/02/24/01004-20090224ARTFIG00277-un-anticorps-humain-pour-combattre-les-grippes-.php

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